Adaptive PhD researcher with 6+ years solving complex formulation challenges through unconventional approaches. Expertise in solubility enhancement, amorphous solid dispersions, and advanced manufacturing technologies transforming drug development from empirical to predictive.
St. John's University (2022-Present): Instructing PharmD students in pharmaceutical manufacturing labs including tablet compression, capsule filling, and quality control. Co-developed Biomedical Chemistry curriculum.
2
Student Research Scientist
University of Mississippi (2019-2021): Maintained mammalian cell cultures, optimized protein extraction protocols for opioid and cannabinoid receptors, and executed radioligand binding assays on 50+ novel compounds.
3
Formulation Development Intern
Glenmark Pharmaceuticals: Developed Atropine HCl nebulizer and nasal formulations. Gained hands-on experience with aerodynamic particle size analysis and ICH stability compliance.
4
Manufacturing Intern
Holden Laboratories: Comprehensive understanding of solid dosage manufacturing, in-process controls, quality assessments, and GMP compliance.
Applied acid-base supersolubilization (ABS) principle for solubility enhancement of BCS Class II/IV APIs using weak acids/bases. Avoided salt precipitation at pHmax, enabling continued solubility increase and superior dissolution performance.
Results
Achieved >85% drug release in 15 minutes using solvent-free spray drying with aqueous ABS solutions. Performed in silico biopharmaceutics modeling using GastroPlus (PBPK, IVIVC); physical characterization using DSC, TGA, XRD, and FTIR, confirming 6+ months stability at 40°C/75% RH per ICH Q1A(R2).
Machine Learning Drives Innovation
Nanosuspension Particle Size Prediction
Developed machine learning models predicting nanosuspension particle size from molecular descriptors by formulating 40 drugs into 3 stabilizer systems (HPMC-SLS, Kollidon K17-Tween 80, Albumin-Tween 80) using wet media milling. Identified formulation-specific molecular "fingerprints," enabling rational drug candidate selection and reducing trial-and-error screening.
IPEC Award
Excellence in Pharmaceutical Excipients Research (2025)
Best Abstract
AAPS PharmSci 360 (2025)
People's Choice
St. John's University Research Month (2024)
Advanced Manufacturing Technologies
3D Printing
Designed tunable drug release systems using FDM technology. Manufactured pharmaceutical filaments via twin-screw HME with optimized mechanical properties and tensile strength.
Hot Melt Extrusion
Pioneered extrusion of pectin and starch through HME for viscosity enhancement. Developed abuse-deterrent extended-release formulations with gel formation and alcohol-resistant profiles.
Spray Drying
Solvent-free spray drying process using aqueous solutions. Achieved superior dissolution performance and stability for poorly water-soluble drugs.
Research Publications & Impact
Published researcher with 5 peer-reviewed publications demonstrating continuous growth in technical communication and pharmaceutical innovation.
Acid-Base Supersolubilization
Raje, V., Lu, I., Keir, R.S., Serajuddin, A.T.M. Development of indomethacin amorphous solid dispersion by applying acid-base supersolubilization (ABS) principle to enable low-temperature hot melt extrusion. SSRN 5405261
Microcrystalline Cellulose
Int J Pharm Excip (2025) - Moisture sorption-desorption analysis of 13 commercial MCC grades across humidity conditions.
3D Printing Technology
Patel, H., Raje, V., Maczko, P., Patel, K. Application of 3D printing technology for the development of dose-adjustable geriatric and pediatric formulation of celecoxib. Int J Pharm 655:123941 (2024)
Molecular Descriptors
Daware, S., Raje, V., Patel, A., Patel, K. Investigating key molecular descriptors affecting particle size: A predictive exemplary approach for self-emulsifying system. Mol Pharm 20(5):2556-67 (2023)
FDM 3D-Printed Tablets
Pharmaceutics (2022) - Tunable drug release systems with novel extrudable polymers.
Technical Expertise
Formulation
Solid dosage forms
HME & spray drying
3D printing (FDM)
Technologies
Amorphous dispersions
SNEDDS
Nanosuspensions
QbD & DoE
Characterization
DSC, TGA, XRD, FTIR
Particle size analysis
Mechanical testing
Dissolution testing
Software
GastroPlus (PBPK)
Design Expert & JMP
Python & KNIME
Regulatory & Compliance Expertise
FDA Compliance
ANDA, bioequivalence, abuse-deterrent formulations, and comprehensive regulatory documentation expertise.
ICH Guidelines
Q1-Q10 implementation, GLP, GMP, CMC, and ICH stability study protocols per Q1A(R2) standards.
DEA Compliance
Schedule II inventory management and federal regulations for controlled substance formulation development.
Education & Credentials
Bachelor of Technology
Pharmaceutical Sciences & Technology, Institute of Chemical Technology (ICT), Mumbai, India (2018)
Master of Science
Pharmaceutical Sciences & Drug Delivery, University of Mississippi (2021). Thesis: Abuse Deterrent Formulation Using Hot Melt Extrusion Technology
PhD in Industrial Pharmacy
Pharmaceutical Sciences, St. John's University, New York (Expected May 2026). Dissertation: Acid-Base Supersolubilization for Solubility Enhancement
Let's Connect
Driven by innovation in pharmaceutical formulation development and committed to advancing drug delivery technologies. Seeking opportunities to apply expertise in solubility enhancement, advanced manufacturing, and predictive modeling to solve real-world pharmaceutical challenges.